Adenoviral Inciting Antigen and Somatic Hypermutation in VITT
Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a rare prothrombotic complication that occurs after adenoviral vector–based vaccination against coronavirus disease 2019.
Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart
Abundant evidence has correlated influenza infection with cardiovascular disease, yet mechanisms linking infection with the heart remain poorly understood.
News
Policy & Recommendations
Call for Action: Life Course Immunisation Strategy
A Seamless Approach to Protection Across All Ages and Risk Groups
“Supporting our systems: Addressing immunosenescence and improving adult immunisation in Europe”
The International Longevity Centre UK (ILCUK) report highlights how Europe's aging population faces increasing health challenges due to immunosenescence, which reduces vaccine effectiveness and increases vulnerability to disease.
Viral Infections and Risk of Cardiovascular Disease: Systematic Review and Meta‐Analysis
In self‐controlled case series studies, laboratory‐confirmed influenza infection was associated with an elevated risk of acute myocardial infarction and stroke during the first 1 month.
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade
Immune checkpoint inhibitors (ICIs) extend survival in many patients with cancer but are ineffective in patients without pre-existing immunity.
Different vaccination debunking interventions: a randomized, controlled experiment estimating “backfiring” and positive effects
Misinformation about vaccines can hinder efforts to increase immunization rates.
Respiratory viral infections awaken metastatic breast cancer cells in lungs
Understanding the mechanisms that disrupt the quiescence of dormant disseminated cancer cells (DCCs) is crucial for addressing metastatic progression.
